WE ARE HIRING!

 Data di pubblicazione: 31/08/2021

Axxam, a leading provider of integrated discovery services for the entire Life Sciences industries, is currently seeking an HTS data analyst to support our HTS Team in the Data Analysis/Compound Management unit.

The candidate will join a consolidated team of scientists with top level experience in assay development, High Throughput Screening (HTS), compound management, and lab automation as well as IT experts who have developed and implemented a set of tools, database systems, and data analysis methodologies.

The candidate will be dedicated to the support of different projects by conducting all aspects of data management, analysis, and reporting. Good communication skills are critical, for both the interaction with the scientists of the team as well as for the interactions and discussions with our international clients. Beside a broad range of knowledge and skills inherent to data analysis methodologies, statistics, data handling, interaction with relational databases, and graphical presentation, the ideal candidate will have a background in biological/biochemical sciences.The successful candidate must have a high level of self-motivation, attention to detail, sense of responsibility, independence, and ability to thrive in a goal and team-oriented setting. Knowledge of scientific programming languages and interfaces would be a plus.

Major responsibilities:

Analyse the results of HTS campaigns, conducted on a very broad variety of assay types among biochemical or cellbased assays with either luminescence or fluorescencebased detections, and generate presentation or written reports in English.

Required knowledge and skills:

• Master’s degree in a relevant field such as Biological Sciences, Chemistry, Computer Sciences
• Advanced level in the use of Microsoft Excel, Word and Power Point
• Experience in data processing, data visualization, data interpretation
• Experience with relational databases (Oracle)
• Drive for attention to detail with excellent problem solving skills and organisational capability
• Working professionally in a highly collaborative environment on multiple tasks, especially under occasional high-pressure situations
• Strong communication skills, fast learner
• Fluent English (spoken and written). Any additional languages knowledge is a plus
• Experience with HTS data processing, analysis, and data management are a plus
• Knowledge of Genedata Screener Data Analysis
• Software is a plus
• Experience in the usage of Prism, and Dotmatics
• Vortex or alternatives similar softwares for data management are a plus
• Good knowledge of Microsoft Access is a plus.

If your background and personal experience fit this profile, please send your complete application, including cover letter, a brief description of your experience, your CV and a list of references to Axxam's on-line contact centre: http://www.axxam.com/careers/job-listing.

Please add to your CV the following statement: "I hereby grant permission to use my personal data in accordance with the Italian Leg. Dec. 196/2003".

 Data di pubblicazione: 31/08/2021

Axxam, a leading provider of integrated discovery services for the entire Life Sciences industries, is currently seeking an enthusiastic, organized, and creative Cell Biologist experienced in human induced pluripotent stem cells (hiPSC) and hiPS-derived cells for our iPSC Unit.

Major responsibilities:

The ideal candidate should have direct working experience in handling hiPSC and related tasks and be familiar with cell-based assay development approaches and in general with cell biology laboratory techniques, including: in vitro drug screening, assay set up, functional studies, phenotypic analysis, genome editing and generation of differentiated cell types, disease modelling.
Activity in the development and validation of miniaturised, functional cell-based assays for HTS using hiPSC derived cells (such as neuronal cells and cardiomyocytes) will be the primary task of the successful candidate.A Ph.D. in Cell Biology/ Molecular Medicine/ Pharmacology is ideal.

Required knowledge and skills:

Candidates must have a thorough understanding and strong practical experience in the followings:

• Expanding hiPSCs in culture and banking hiPSCs for research use
• Maintenance and scale up cultures for hiPSCs and their differentiation toward different lineages, such as neuronal cells and cardiomyocytes
• Development of disease modelling assays through assessment of physiologically relevant Phenotypes
• Development of cell-based assays, for different targets and using different readout systems
• Setting up, maintaining, and efficiently operating cost -effective laboratory operations
• Familiarity with basic pharmacological concepts for receptors, ion channels and transporters.
• Evaluate, analyse and interpret research data
• Ability to follow instruction closely, but also to work independently as required
• Good team player
• Ability to work to tight deadlines with a sense of urgency.
• Working knowledge of Microsoft Office programs (Excel, Word, PowerPoint)
• Use of GraphPad Prism
• Fluent/good spoken and written English.

The following skills would be advantageous:

• Genome editing of hiPSC lines for mutation introduction and correction, KI, KO, reporter gene insertion
• Immunohistochemistry and phenotypic analysis
• Familiarity with lab automation: micro titer plates and liquid-handling devices
• Preparation of cells to meet the demands of multiple projects.

If your background and personal experience fit this profile, please send your complete application, including cover letter, a brief description of your experience, your CV and a list of references to Axxam's on-line contact centre: http://www.axxam.com/careers/job-listing.

Please add to your CV the following statement: "I hereby grant permission to use my personal data in accordance with the Italian Leg. Dec. 196/2003".

 Data di pubblicazione: 06/08/2021

Axxam, a leading provider of integrated discovery services for the entire Life Sciences industries, is looking for an enthusiastic, organized, and creative cell- biologist for their High Throughput Screening Group.

The ideal candidate will be a motivated and expert scientist who can support miniaturization and adaption of cell-based assays for HTS, HTS routine activities as well as mechanism of action studies to enable SAR development.

Experience with HTS, fluorescence- and luminescent-based assays, liquid handling automation are desirable.

This position will work as part of a team, following detailed laboratory protocols and analyzing data, to deliver high quality, timely data to customers.

Major responsibilities:

• adaption of cell-based assays to HTS automated station
• run high throughput screening and compound profiling projects utilizing state-of-the-art automated screening stations in 384 formats with general instruction, good consistency, and strong attention to detail
• perform data analysis and create reports using established software tools and systems
• identify potential problems that may affect quality, accuracy, and usefulness of data in screening assays and provide ideas for solutions
• evaluate, analyse and interpret research data
• present data to clients
• write reports for clients
• respond to changing priorities and handle multiple projects with overlapping deadlines. Demonstrate a strong sense of urgency to deliver quality results to customers by defined deadlines
• ensure support to colleagues for collaborative projects, and reliability, accuracy, robustness and high quality for data and reports
• ability to quickly learn and adapt to new processes

Required knowledge and skills:

• relevant experience in assay design, in assay execution and possibly in screening, preferably in industry and/or service-oriented organisation
• experience in using liquid handling and automated screening stations is a very preferable skill
• relevant experience and strong working knowledge of in vitro detection technologies
• experience in leading client projects. Analyse, summarize and interpret data and provide written and verbal updates to clients in timely manner
• proficiency in Microsoft Word, Excel and PowerPoint. Knowledge of GraphPad Prism and other data analysis software are a plus
• a self-motivated individual that can function both independently as well as part of a team
• ability to work effectively under strict deadlines within a team framework in cross-functional projects as well as independent scientist
• ensure support to colleagues for collaborative projects, and reliability, accuracy, robustness and high quality for data and reports
• effective communications with colleagues at all levels and with external international partners
• adherence to protocols and to corporate policies on Quality and Health & Safety
• fluency in English, written and spoken
• PhD in Biotechnology / Cell biology or other related discipline is welcome.

If your background and personal experience fit this profile, please send your complete application, including cover letter, a brief description of your experience, your CV and a list of references to Axxam's on-line contact centre: http://www.axxam.com/careers/job-listing.

Please add to your CV the following statement: "I hereby grant permission to use my personal data in accordance with the Italian Leg. Dec. 196/2003".

 Data di pubblicazione: 30/07/2021

Principali responsabilità:

• Esecuzione della strategia di marketing e comunicazione attraverso compiti e scadenze specifiche
• Monitorare le attività in corso con lo strumento di gestione dei progetti aziendali
• Co-creazione di materiali di re-branding aziendale
• Revisione dei materiali e delle presentazioni aziendali assicurando che le linee guida del marchio aziendale siano sempre presenti
• Monitorare le campagne di marketing in corso organizzando i dati in specifici report di analisi
• Gestione degli strumenti di automazione
• Co-gestione del database degli HCP e della piattaforma CRM
• Ricerca e monitoraggio continuo delle attività e delle iniziative della concorrenza
• Ricerca continua online e offline eseguita per raggiungere specifici obiettivi e risultati mirati
• Gestire gli aspetti creativi e logistici di omaggi, attività di prodotti di marca per campagne di sampling
• Coordinamento della partecipazione di Silk Biomaterials a congressi scientifici in Europa e USA
• Coordinamento della creazione di materiali di marketing del prodotto
• Monitorare le campagne di marketing online e offline e riportare i risultati confrontandoli con i KPI precedentemente definiti
• Revisione delle presentazioni dei prodotti per eventi aziendali o eventi di terzi assicurando che le linee guida del marchio siano sempre presenti

Il candidato ideale è:

• Un apprendista molto veloce, divertente e con cui sia facile collaborare
• Proattivo, pragmatico e orientato agli obiettivi
• Creativo e appassionato di design
• Appassionato di marketing digitale, analisi dei dati e reporting
• Versatile e dinamico
• Lavoratore instancabile e collaborativo

Requisiti aggiuntivi:

• Laurea in economia, finanza, amministrazione aziendale o campi correlati
• Alta conoscenza della lingua inglese

È possibile inoltrare la propria candidatura scrivendo a gabriella@silkbiomaterials.com

 Data di pubblicazione: 26/07/2021

Axxam, a leading provider of integrated discovery services for the entire Life Sciences industries, is looking for a High Content Screening Scientist to strengthen its image and cell-based assay development capabilities for its customer projects. Development and validation of miniaturised, phenotypic cell-based assays for high and medium -throughput screening will be the primary activity of the successful candidate.

Candidates must have a PhD and a thorough understanding of cellular functional assays using mammalian cells and imaging approach, specifically:

• a Ph.D. in biophysics, pharmacology, biotechnology or proven track records and experience in any, but not limiting, of the following fields: autophagy, organelle biogenesis (mitochondrion, nucleus, lysosome), inflammatory pathways, fibrotic pathways, cell differentiation (muscle, neuron)
• skills and research experience applicable to target identification, mechanism-of-action/pathway analysis, and development of cellular assays suitable for imaging applications applying siRNA, shRNA or CRISPR technologies
• relevant experience in recombinant gene expression in mammalian cells using electroporation, lipofection, or other methods
• proven experience in immunofluorescence-based and staining preparation of the samples in miniaturized formats (96-384 well formats)
• proven knowledge of confocal and wide-field microscopy.

The following technical skills would be a plus:

• knowledge of image analysis and data analysis software (e.g. ImageJ/Fiji, MetaMorph, Harmony, R, GraphPad) hands on 3D cell cultures, spheroids imaging
• experience with Optogenetic approaches
• familiarity with lab automation: plates and liquid-handling devices, 96 and 384 well format.

The following soft skills would be advantageous:

• propensity for laboratory work
• strong problem solving
• good mindset for data analysis
• strong team player skills and ability to interact with colleagues and clients
• ability to present results internally and externally in timely and clear manner
• ability to work to tight deadlines
• ability to follow instruction closely, but also to work independently and to be proactive in bringing new ideas and solutions
• multi-focus capability on several projects
• fluent/good spoken and written English.

If your background and personal experience fit this profile, please send your complete application, including cover letter, a brief description of your experience, your CV and a list of references to Axxam's on-line contact centre: http://www.axxam.com/careers/job-listing.

Please add to your CV the following statement: "I hereby grant permission to use my personal data in accordance with the Italian Leg. Dec. 196/2003".

 Data di pubblicazione: 15/07/2021

Axxam, a leading provider of integrated discovery services for the entire Life Sciences industries, is looking for a Molecular Biology Scientist with a strong background in molecular biology concepts such as gene regulation, splicing, epigenetics, RNA biology and genetically encoded reporters (e.g. GFPs; luciferases etc.) and good experience in:

• Gene expression analysis, RNA isolation, RT-qPCR (from primer design to data analysis, in particular with TaqMan assays).
• Genomic analysis, genome browser software tools, CRISPR/Cas9 genome editing.
• Cloning, plasmid-based constructs design and generation, DNA preparations.
• Using databases for DNA and protein analysis.
• Sanger and NGS technologies, bioinformatics data analysis.

Main activities:

She/he will join a team of scientists responsible for the development of the molecular biology tools necessary for executing cell-based and biochemical assays. She/he will be expected to strictly adhere to company SOPs when performing lab functions, maintanining paperwork and batch records. Willing to perform high-profile molecular biology projects, as well as routine tasks.

The following skills would be advantageous:

• Good team player.
• Ability to work to tight deadlines with a sense of urgency.
• Ability to follow instruction closely, but also to work independently as required.
• Capability to implement approaches from literature.
• Practice with set up and data output of TaqMan based RNA analysis.
• Knowledge of high throughput RNA expression analysis as Chip and RNA-Seq technologies.
• Practice with automated liquid handling systems.
• Attitude towards automated processes.
• Knowledge of Microsoft Access database.
• Experience in recombinant protein expression or generation of stable cells.
• Good spoken and written English.
• Good presentation skills.

If your background and personal experience fit this profile, please send your complete application, including cover letter, a brief description of your experience, your CV and a list of references to Axxam's on-line contact centre: http://www.axxam.com/careers/job-listing.

Please add to your CV the following statement: "I hereby grant permission to use my personal data in accordance with the Italian Leg. Dec. 196/2003".

                                                    Data di pubblicazione:  06/07/2021

Enthera, a biotech company building a pipeline of first-in-class biologics for several underserved autoimmune conditions, is looking for a Development Scientist - Biologics.

Data di pubblicazione: 11/06/2021

AGC Biologics, azienda leader nella Cell & Gene Therapy sta ricercando un tecnico da inserire nel gruppo di GMP Manufacturing.

Attività principali

• Mantenimento in coltura ed espansione di linee cellulari adese e in sospensione: manipolazione in asepsi di fiasche, cell factories e sacche;
• Criopreservazione di banche cellulari (Master cell bank e Warking cell bank);
• Isolamento di cellule mononucleate da sangue periferico o da espianto midollare mediante separazione su gradiente di Ficoll;
• Selezione di cellule staminali ematopoietiche da aferesi o espianto midollare mediante separazione immunomagnetica;
• Produzione vettori Retro- e Lenti-virali;
• Redazione e mantenimento della documentazione correlata alle attività GMP manufacturing: Batch Record, SOPs, protocolli, report;
• Gestione della documentazione relativa alle Quality Deviation, Change.

Requisiti

• Laurea in Biotecnologie o similari;
• Esperienza pregressa nelle tecniche sopraelencate;
• Preferibile esperienza in cleanroom e familiarità con le GMP.

È possibile inoltrare la propria candidatura scrivendo a Hr.it@agcbio.com.

Data di pubblicazione: 11/06/2021

AGC Biologics, azienda leader nella Cell & Gene Therapy, sta ricercando un Purchasing Supervisor.

Attività principali

• Supervisione degli ordini d'acquisto nel rispetto delle scadenze e delle procedure interne
• Ispezionare e valutare la qualità degli articoli acquistati e risolvere le carenze in collaborazione con il Quality Assurance Department;

• Monitoraggio delle prestazioni dei fornitori e risoluzione di problemi e criticità;

• Ricerca e identificazione di potenziali fornitori;

• Valutare i prodotti e i fornitori in base a criteri aziendali chiave;

• Analizzare l'industria e le tendenze della domanda e sostenere il senior management nello sviluppo e nell'implementazione delle strategie di sourcing;

• Coordinare il team degli acquisti e le loro attività.

Requisiti

• Laurea in economia o similari;
• Almeno 5 anni di esperienza nello stesso ruolo all'interno di imprese farmaceutiche;
• Esperienza nel lavorare con sistemi di ERP, MSAX e l'ecosistema Microsoft Office;
• Inglese fluente;
• Forti capacità organizzative e di negoziazione, pensiero analitico e problem solving;
• Abilità nel lavorare sotto pressione.

È possibile inoltrare la propria candidatura scrivendo a Hr.it@agcbio.com.

                                                     Data di pubblicazione: 29/06/2021

Zambon is looking for a Digital & Multichannel Specialist who will report to the Head of Business Operations of Zambon Italy

Responsabilities:

• Contribute to the definition of the omnichannel customer engagement strategy in order to maximise the HCP experience
• Co-ordinate and contribute to the development and implementation of the content strategy and engagement plan process to ensure alignment with brand objectives, customer personas and channel mix
• Develop and drive the implementation of digital & multichannel tactics (eg email marketing campaigns, approved email, web portals, seo/sem) in collaboration with brand managers and sales colleagues
• Work with Global and Local functions (eg. Marketing & Sales, Medical, Legal & Compliance, IT) to ensure alignment of strategies and tactics and excellence in execution
• Work with Legal Department and Compliance to ensure that projects within the scope of digital & multichannel are fully compliant with local laws and company rules.
• Proactively collaborate to the business' strategy and decisions with an integrated omnichannel approach
• Manage the activation of new channels managing the relationship with Global teams and agencies or local vendors, coordinating the process and involving the needed local functions
• Collaborate with the analytics team on digital&multichannel measurement plans, selecting KPIs and setting goals, targets and measurement milestones for each channel included in the tactics developed
• Ensure all digital marketing activities are tracked, reported and presented back to the business to facilitate continual learning and improvement
• Lead on the ideation process for proposed omnichannel solutions and strategies (utilising the principles of agility and customer centricity)
• Promote the digital culture inside the Company and keep up with the latest digital trends
• Leverages and contributes to expertise, best-practices, and benchmarks in designing effective Multichannel programs and campaigns
• Ensure excellence in execution of activities across all digital channels, leading to an exceptional Customer Experience

Requirements:

• 3-5 years of digital & multichannel customer engagement experience, ideally in marketing agencies or pharmaceuticals
• Past experience in designing & implementation of multichannel campaigns and initiatives in the pharmaceutical market
• CRM experience preferred, marketing automation preferred experience, email marketing tool experience, website design experience, knowledge SEO and SEM principles
• Master degree in Engineering / Economics or equivalent (preferable specialization in digital marketing)
• Good knowledge of English

You can submit your application by visiting this link.

 Data di pubblicazione: 29/06/2021

Zambon is looking for a Senior Buyer – Real Estate & General Services who will support the Head of Indirect Procurement in managing the purchases for general services and new real estate project of the Company.

Responsibilities:

You will be accountable for the delivery of key objectives and process improvements, with a cost and quality monitoring and you will be responsible for the following activities:

• To constantly monitor and manage the Company spend and Indirect categories assigned
• To Identify and manage new categories to be addressed and support new procurement culture implementation
• To support and implement procurement strategies and initiatives: performing competitive sourcing activities, searching of new potential suppliers, managing tenders and negotiating.
• To manage supplier relationships and performance and to build effective partnerships
• To manage and negotiate, in collaboration with legal dep. supply contracts, to ensure full compliance with the Company guidelines and standards
• To implement knowledge and share information about procurement best practices and innovative ideas
• To monitor supplier’s performance also for post-contract’s performance
• To liaise with internal customer departments as well as Legal and Finance and providing proactive support
• To prepare and manage the assigned category budget
• To monitor procurement costs.

Requirements:

• At least 5 years in the role in a complex environment.
• Excellent negotiation, networking skills and problem-solving capabilities, customer oriented
• Proactive, motivated and with a positive attitude
• Ability to manage a team and to work with cross-functional team within the organization
• Excellent computer skills, proficient in MS Office (Excel, Power Point, etc), Stealth, Esker & SAP is a plus,
• SAP ARIBA certified users is nice to have
• You are a team player, proactive and with strong interpersonal and communication skills,
• You are fluent in Italian and English

You can submit your application by visiting this link.

Data di pubblicazione: 01/06/2021

OpenZone è alla ricerca di un Facility Specialist da inserire nella propria struttura operativa.

Attività principali

A diretto riporto del Facility Manager di OpenZone, il Facility Specialist:

• Presidia la gestione degli spazi, degli allestimenti, delle attrezzature, delle attività manutentive ed i servizi affidati alle società esterne.
• Gestisce i contratti di manutenzione impiantistica (impianti HVAC, Aspirazione, Gas) sotto l’aspetto elettrico, meccanico e di controllo elettronico degli apparati.
• Si interfaccia con stakeholder e clienti interni per l’organizzazione degli interventi di manutenzione programmata ordinaria e straordinaria concordandone tempi e modi, in funzione di eventuali particolari profili esigenziali, e reportizzandone gli esiti
• Gestisce e supervisiona il piano di manutenzione in accordo con il FM.
• Formula proposte migliorative sulla base delle evidenze emerse dal piano di manutenzione e degli eventi verificatisi.
• Agevola la raccolta delle esigenze per la redazione del budget e la sua revisione periodica in materia di Facility e provvede ad allocarle nei corretti centri di costo.
• Conserva la documentazione delle lavorazioni, le certificazioni previste per impianti, finiture ed attrezzature e ne organizza l’archivio.
• Supporta l’HSE ed il RSPP nell’applicazioni delle disposizioni di legge in materia di sicurezza degli ambienti di lavoro.
• Monitora, anche da remoto, attraverso sistemi di BMS (regolazione microlima e temperature etc.) i parametri ambientali intervenendo per modificarli.
• Effettua rilevazioni strumentali ambientali in campo.
• Fornisce supporto tecnico durante le attività di ristrutturazione.
• Interagisce con altre funzioni aziendali su richiesta

Requisiti

• Laurea in Ingegneria o Architettura o diploma tecnico
• Almeno 3-5 anni di esperienza in ruoli simili
• Esperienza pregressa nella gestione e supervisione dei sistemi di impiantistica
• Preferibile l'esperienza nella manutenzione di laboratori di ricerca
• Conoscenza di aspetti di Health & Safety nei luoghi di lavoro
• Buona conoscenza di excel
• Conoscenza fluente della lingua inlese (almeno livello B2)
• Conoscenze di base di AUTOCAD, CAD BIM (per building automation/integrazione con app per gestione del building/data driven)
• Conoscenze normative in ambito Facility (a titolo esemplificativo ISO 27001, ISO 22301 BUSINESS CONTINUITY ETC).
• Conoscenza di base di GESTIONE PROGETTO E “TPM – Total Productivity Maintenance”
• Conoscenza dei princpi della TRIGENERAZIONE

È possibile inoltrare la propria candidatura visitando questo link.