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March 2022

European Investment Bank to Provide a €7.5 Million Loan to Support Further Research and Development of Diadem's AlzoSure® Predict Blood Test for Alzheimer's Disease

The European Investment Bank (EIB) has awarded a €7.5 million loan to Diadem, a company developing the first blood-based prognostic test for the early prediction of Alzheimer's disease (AD). The loan granted under the Pan European Guarantee Fund's Venture Debt programme, an integral part of the €540 billion EU aid package agreed in 2020 to counter the economic crisis caused by the COVID pandemic, is intended to support the development and commercialization of Diadem's AlzoSure® Predict prognostic blood test for the early detection of Alzheimer's disease.

Headquartered at OpenZone campus, Diadem was founded in 2012 as a spin-out of the University of Brescia (Italy), with the support of the Italian Ministry of Education, Universities and Research. It is considered to be one of the most promising Italian biotech SMEs (small and mid-size enterprises).


AlzoSure® Predict is a non-invasive biomarker blood test that can identify with high accuracy whether individuals over the age of 50 with signs of cognitive impairment will or will not progress to Alzheimer's disease up to six years before definitive symptoms are apparent.

Its utility is supported by clinical data from a large longitudinal study that was the basis for AlzoSure® Predict's recent CE-IVD marking, which allows the test to be marketed in the EU, as well as for a Breakthrough Device designation from the U.S. Food & Drug Administration.
 
Gelsomina Gigliotti
EIB Vice-President

 

Diagnostics for neurodegenerative conditions such as Alzheimer's disease have not been able to identify patients early enough in the disease process to allow interventions to slow or stop disease progression. With this investment, the EIB is confirming its commitment to research and to companies such as Diadem that are at the forefront of biotechnology innovation. We expect this EIB funding will help contribute to a revolution in Alzheimer's disease diagnostics, through the ability of AlzoSure® Predict to enable precise and early prediction of which individuals will progress to Alzheimer's disease.

 

Paul Kinnon
CEO at Diadem

 

 

As a company whose innovative technology was discovered and developed in Italy, we are proud to receive this vote of confidence and financial support from EIB. We believe AlzoSure® Predict represents a significant advance for the millions of patients in Europe at risk from Alzheimer's disease. Earlier knowledge will benefit those individuals found to be at risk, who can now take steps to slow the progression of the disease, as well as those who are found to be at low risk of advancing to AD. We also expect that the availability of AlzoSure® Predict will facilitate the development of promising new therapies. Diadem intends to partner with health providers to ensure wide access to AlzoSure® Predict and we expect the test to be available in the EU later this year.

 

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